TAB2 Is Essential for Prevention of Apoptosis in Fetal Liver but Not for Interleukin-1 Signaling

The proinflammatory cytokine interleukin-1 (IL-1) transmits a signal via several critical cytoplasmic proteins such as MyD88, IRAKs and TRAF6. Recently, serine/threonine kinase TAK1 and TAK1 binding protein 1 and 2 (TAB1/2) have been identified as molecules involved in IL-1-induced TRAF6-mediated ac...

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Autores principales: Sanjo, Hideki, Takeda, Kiyoshi, Tsujimura, Tohru, Ninomiya-Tsuji, Jun, Matsumoto, Kunihiro, Akira, Shizuo
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
Materias:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC141141/
https://ncbi.nlm.nih.gov/pubmed/12556483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.4.1231-1238.2003
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