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Ketolide Antimicrobial Activity Persists after Disruption of Interactions with Domain II of 23S rRNA
Ketolides are the latest derivatives developed from the macrolide erythromycin to improve antimicrobial activity. All macrolides and ketolides bind to the 50S ribosomal subunit, where they come into contact with adenosine 2058 (A2058) within domain V of the 23S rRNA and block protein synthesis. An a...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2004
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC521900/ https://ncbi.nlm.nih.gov/pubmed/15388419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.10.3677-3683.2004 |
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