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Molecular Mechanisms by Which rRNA Mutations Confer Resistance to Clindamycin

The mechanisms by which rRNA mutations confer clindamycin resistance were examined in Mycobacterium smegmatis strains containing homogeneous populations of ribosomes with base substitutions at nucleotides A2058 and A2059. Computer graphic predictions based on structural studies correlate with the re...

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Détails bibliographiques
Auteurs principaux: Poehlsgaard, Jacob, Pfister, Peter, Böttger, Erik C., Douthwaite, Stephen
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1068640/
https://ncbi.nlm.nih.gov/pubmed/15793137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.4.1553-1555.2005
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