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Molecular Mechanisms by Which rRNA Mutations Confer Resistance to Clindamycin

The mechanisms by which rRNA mutations confer clindamycin resistance were examined in Mycobacterium smegmatis strains containing homogeneous populations of ribosomes with base substitutions at nucleotides A2058 and A2059. Computer graphic predictions based on structural studies correlate with the re...

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Bibliografische gegevens
Hoofdauteurs: Poehlsgaard, Jacob, Pfister, Peter, Böttger, Erik C., Douthwaite, Stephen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2005
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1068640/
https://ncbi.nlm.nih.gov/pubmed/15793137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.4.1553-1555.2005
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