Molecular Mechanisms by Which rRNA Mutations Confer Resistance to Clindamycin

The mechanisms by which rRNA mutations confer clindamycin resistance were examined in Mycobacterium smegmatis strains containing homogeneous populations of ribosomes with base substitutions at nucleotides A2058 and A2059. Computer graphic predictions based on structural studies correlate with the re...

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Autores principales: Poehlsgaard, Jacob, Pfister, Peter, Böttger, Erik C., Douthwaite, Stephen
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Mechanisms of Resistance
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1068640/
https://ncbi.nlm.nih.gov/pubmed/15793137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.4.1553-1555.2005
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