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Activity of the Ketolide Telithromycin Is Refractory to Erm Monomethylation of Bacterial rRNA

Methylation of specific nucleotides in rRNA is one of the means by which bacteria achieve resistance to macrolides-lincosamides-streptogramin B (MLS(B)) and ketolide antibiotics. The degree of resistance is determined by how effectively the rRNA is methylated. We have implemented a bacterial system...

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Autors principals: Liu, Mingfu, Douthwaite, Stephen
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC127225/
https://ncbi.nlm.nih.gov/pubmed/12019067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.6.1629-1633.2002
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