Identification of Essential Residues in the Erm(B) rRNA Methyltransferase of Clostridium perfringens

Macrolide-lincosamide-streptogramin B resistance is widespread, with the determinants encoding resistance to antibiotics such as erythromycin being detected in many bacterial pathogens. Resistance is most commonly mediated by the production of an Erm protein, a 23S rRNA methyltransferase. We have un...

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Main Authors: Farrow, Kylie A., Lyras, Dena, Polekhina, Galina, Koutsis, Katerina, Parker, Michael W., Rood, Julian I.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2002
Assuntos:
Mechanisms of Resistance
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC127184/
https://ncbi.nlm.nih.gov/pubmed/11959553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.5.1253-1261.2002
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