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Activity of the Ketolide Telithromycin Is Refractory to Erm Monomethylation of Bacterial rRNA

Methylation of specific nucleotides in rRNA is one of the means by which bacteria achieve resistance to macrolides-lincosamides-streptogramin B (MLS(B)) and ketolide antibiotics. The degree of resistance is determined by how effectively the rRNA is methylated. We have implemented a bacterial system...

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Detalhes bibliográficos
Main Authors: Liu, Mingfu, Douthwaite, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127225/
https://ncbi.nlm.nih.gov/pubmed/12019067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.6.1629-1633.2002
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