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ERK1/2/MAPK pathway-dependent regulation of the telomeric factor TRF2
Telomere stability is a hallmark of immortalized cells, including cancer cells. While the telomere length is maintained in most cases by the telomerase, the activity of a protein complex called Shelterin is required to protect telomeres against unsuitable activation of the DNA damage response pathwa...
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| 發表在: | Oncotarget |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Impact Journals LLC
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5216822/ https://ncbi.nlm.nih.gov/pubmed/27366950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10316 |
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