ERK1/2/MAPK pathway-dependent regulation of the telomeric factor TRF2

Telomere stability is a hallmark of immortalized cells, including cancer cells. While the telomere length is maintained in most cases by the telomerase, the activity of a protein complex called Shelterin is required to protect telomeres against unsuitable activation of the DNA damage response pathwa...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Picco, Vincent, Coste, Isabelle, Giraud-Panis, Marie-Josèphe, Renno, Toufic, Gilson, Eric, Pagès, Gilles
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216822/
https://ncbi.nlm.nih.gov/pubmed/27366950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10316
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