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Protein evolution by codon-based random deletions
A method to delete in-phase codons throughout a defined target region of a gene has been developed. This approach, named the codon-based random deletion (COBARDE) method, is able to delete complete codons in a random and combinatorial mode. Robustness, automation and fine-tuning of the mutagenesis r...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC521680/ https://ncbi.nlm.nih.gov/pubmed/15459282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh135 |
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