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Protein evolution by codon-based random deletions

A method to delete in-phase codons throughout a defined target region of a gene has been developed. This approach, named the codon-based random deletion (COBARDE) method, is able to delete complete codons in a random and combinatorial mode. Robustness, automation and fine-tuning of the mutagenesis r...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Principais autores: Osuna, Joel, Yáñez, Jorge, Soberón, Xavier, Gaytán, Paul
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2004
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC521680/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15459282/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gnh135
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