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Protein evolution by codon-based random deletions

A method to delete in-phase codons throughout a defined target region of a gene has been developed. This approach, named the codon-based random deletion (COBARDE) method, is able to delete complete codons in a random and combinatorial mode. Robustness, automation and fine-tuning of the mutagenesis r...

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Detalhes bibliográficos
Main Authors: Osuna, Joel, Yáñez, Jorge, Soberón, Xavier, Gaytán, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC521680/
https://ncbi.nlm.nih.gov/pubmed/15459282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh135
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