Laddar...
The role of break-induced replication in large-scale expansions of (CAG)(n)•(CTG)(n) repeats
Expansions of (CAG)(n)•(CTG)(n) trinucleotide repeats are responsible for over a dozen neuromuscular and neurodegenerative disorders. Large-scale expansions are typical for human pedigrees and may be explained by iterative small-scale events such as strand slippage during replication or repair DNA s...
Sparad:
| I publikationen: | Nat Struct Mol Biol |
|---|---|
| Huvudupphovsmän: | , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2016
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5215974/ https://ncbi.nlm.nih.gov/pubmed/27918542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3334 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|