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The role of break-induced replication in large-scale expansions of (CAG)(n)•(CTG)(n) repeats
Expansions of (CAG)(n)•(CTG)(n) trinucleotide repeats are responsible for over a dozen neuromuscular and neurodegenerative disorders. Large-scale expansions are typical for human pedigrees and may be explained by iterative small-scale events such as strand slippage during replication or repair DNA s...
Tallennettuna:
| Julkaisussa: | Nat Struct Mol Biol |
|---|---|
| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2016
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5215974/ https://ncbi.nlm.nih.gov/pubmed/27918542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3334 |
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