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A balance between elongation and trimming regulates telomere stability in stem cells

Telomere length maintenance ensures self-renewal of human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs), however the mechanisms governing telomere length homeostasis in these cell types are unclear. Here, we report that telomere length is determined by the balance between t...

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Vydáno v:Nat Struct Mol Biol
Hlavní autoři: Rivera, Teresa, Haggblom, Candy, Cosconati, Sandro, Karlseder, Jan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215970/
https://ncbi.nlm.nih.gov/pubmed/27918544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3335
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