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A Balance between Tel1 and Rif2 Activities Regulates Nucleolytic Processing and Elongation at Telomeres
Generation of G-strand overhangs at Saccharomyces cerevisiae yeast telomeres depends primarily on the MRX (Mre11-Rad50-Xrs2) complex, which is also necessary to maintain telomere length by recruiting the Tel1 kinase. MRX physically interacts with Rif2, which inhibits both resection and elongation of...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3347235/ https://ncbi.nlm.nih.gov/pubmed/22354991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06547-11 |
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