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Cell Death During Crisis Is Mediated by Mitotic Telomere Deprotection
Tumour formation is blocked by two barriers, replicative senescence and crisis(1). Senescence is triggered by short telomeres and is bypassed by disruption of tumour suppressive pathways. After senescence bypass, cells undergo crisis, during which almost all of the cells in the population die. Cells...
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| 出版年: | Nature |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4481881/ https://ncbi.nlm.nih.gov/pubmed/26108857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14513 |
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