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The telomere deprotection response is functionally distinct from the genomic DNA damage response

Loss of chromosome end protection through telomere erosion is a hallmark of aging and senescence. Here we developed an experimental system that mimics physiological telomere deprotection in human cells and discovered that the telomere deprotection response is functionally distinct from the genomic D...

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Detalles Bibliográficos
Main Authors: Cesare, Anthony J., Hayashi, Makoto T., Crabbe, Laure, Karlseder, Jan
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721072/
https://ncbi.nlm.nih.gov/pubmed/23850488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.06.006
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