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The telomere deprotection response is functionally distinct from the genomic DNA damage response
Loss of chromosome end protection through telomere erosion is a hallmark of aging and senescence. Here we developed an experimental system that mimics physiological telomere deprotection in human cells and discovered that the telomere deprotection response is functionally distinct from the genomic D...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3721072/ https://ncbi.nlm.nih.gov/pubmed/23850488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.06.006 |
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