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Cell Death During Crisis Is Mediated by Mitotic Telomere Deprotection
Tumour formation is blocked by two barriers, replicative senescence and crisis(1). Senescence is triggered by short telomeres and is bypassed by disruption of tumour suppressive pathways. After senescence bypass, cells undergo crisis, during which almost all of the cells in the population die. Cells...
में बचाया:
| में प्रकाशित: | Nature |
|---|---|
| मुख्य लेखकों: | , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2015
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4481881/ https://ncbi.nlm.nih.gov/pubmed/26108857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14513 |
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