Mutational landscape and gene-expression patterns in adult acute myeloid leukemias with monosomy 7 as a sole abnormality

Monosomy of chromosome 7 is the most frequent autosomal monosomy in acute myeloid leukemia (AML), where it associates with poor clinical outcomes. However, molecular features associated with this sole monosomy subtype (-7 AML) which may give insights into the basis for its poor prognosis have not be...

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Gepubliceerd in:Cancer Res
Hoofdauteurs: Eisfeld, Ann-Kathrin, Kohlschmidt, Jessica, Mrózek, Krzysztof, Volinia, Stefano, Blachly, James S., Nicolet, Deedra, Oakes, Christopher, Kroll, Karl, Orwick, Shelley, Carroll, Andrew J., Stone, Richard M., Byrd, John C., de la Chapelle, Albert, Bloomfield, Clara D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215102/
https://ncbi.nlm.nih.gov/pubmed/27784745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-1386
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