Adult acute myeloid leukemia with trisomy 11 as the sole abnormality is characterized by the presence of five distinct gene mutations: MLL-PTD, DNMT3A, U2AF1, FLT3-ITD and IDH2

Eitemau Tebyg

• Clinical and molecular characterization of patients with acute myeloid leukemia and sole trisomies of chromosomes 4, 8, 11, 13 or 21
  gan: Bhatnagar, Bhavana, et al.
  Cyhoeddwyd: (2019)
• Mutational landscape and gene-expression patterns in adult acute myeloid leukemias with monosomy 7 as a sole abnormality
  gan: Eisfeld, Ann-Kathrin, et al.
  Cyhoeddwyd: (2016)
• Persistence of DNMT3A R882 mutations during remission does not adversely affect outcomes of patients with acute myeloid leukaemia
  gan: Bhatnagar, Bhavana, et al.
  Cyhoeddwyd: (2016)
• Prognostic gene mutations and distinct gene- and microRNA-expression signatures in acute myeloid leukemia with a sole trisomy 8
  gan: Becker, Heiko, et al.
  Cyhoeddwyd: (2014)
• Eradicating acute myeloid leukemia in a Mll(PTD/wt):Flt3(ITD/wt) murine model: a path to novel therapeutic approaches for human disease
  gan: Bernot, Kelsie M., et al.
  Cyhoeddwyd: (2013)