Chronic Lymphocytic Leukemia: Exploiting Vulnerabilities with Targeted Agents

מאת Maly, Joseph, Blachly, James S.
הוצא לאור ב Curr Hematol Malig Rep (2016)

Emerging Drug Profile: Cyclin-Dependent Kinase Inhibitors

מאת Blachly, James S., Byrd, John C.
יצא לאור 2013

Quantifying Hematopoietic Stem Cell Clonal Diversity by Selecting Informative Amplicon Barcodes

מאת Teets, Emily M., Gregory, Charles, Shaffer, Jami, Blachly, James S., Blaser, Bradley W.
הוצא לאור ב Sci Rep (2020)

Co-Treatment of Hairy Cell Leukemia and Melanoma with the BRAF Inhibitor Dabrafenib

מאת Blachly, James S., Lozanski, Gerard, Lucas, David M., Grever, Michael R., Kendra, Kari, Andritsos, Leslie A.
הוצא לאור ב J Natl Compr Canc Netw (2015)

MuCor: mutation aggregation and correlation

מאת Kroll, Karl W., Eisfeld, Ann-Katherin, Lozanski, Gerard, Bloomfield, Clara D., Byrd, John C., Blachly, James S.
הוצא לאור ב Bioinformatics (2016)

Transcriptionally Active Androgen Receptor Splice Variants Promote Hepatocellular Carcinoma Progression

מאת Dauki, Anees M., Blachly, James S., Kautto, Esko A., Ezzat, Sameera, Abdel-Rahman, Mohamed H., Coss, Christopher C.
הוצא לאור ב Cancer Res (2019)

Characterization and mitigation of fragmentation enzyme-induced dual stranded artifacts

מאת Gregory, Thomas, Ngankeu, Apollinaire, Orwick, Shelley, Kautto, Esko A, Woyach, Jennifer A, Byrd, John C, Blachly, James S
הוצא לאור ב NAR Genom Bioinform (2020)

Classic hairy cell leukemia complicated by pancytopenia and severe infection: a report of 3 cases treated with vemurafenib

מאת Shenoi, Daniel P., Andritsos, Leslie A., Blachly, James S., Rogers, Kerry A., Moran, Mollie E., Anghelina, Mirela, Jones, Jeffrey A., Grever, Michael R.
הוצא לאור ב Blood Adv (2019)

Reduced dose pentostatin for initial management of hairy cell leukemia patients who have active infection or risk of hemorrhage is safe and effective

מאת Andritsos, Leslie A., Dunavin, Neil, Lozanski, Gerard, Jones, Jeffrey A., Blachly, James S., Lucas, David M., Byrd, John C., Kraut, Eric, Grever, Michael R.
הוצא לאור ב Haematologica (2015)

Cotargeting of XPO1 Enhances the Antileukemic Activity of Midostaurin and Gilteritinib in Acute Myeloid Leukemia

מאת Brinton, Lindsey T., Sher, Steven, Williams, Katie, Canfield, Daniel, Orwick, Shelley, Wasmuth, Ronni, Cempre, Casey, Skinner, Jordan, Lehman, Amy, Blachly, James S., Byrd, John C., Lapalombella, Rosa
הוצא לאור ב Cancers (Basel) (2020)

Quality Control for RNA-Seq (QuaCRS): An Integrated Quality Control Pipeline

מאת Kroll, Karl W, Mokaram, Nima E, Pelletier, Alexander R, Frankhouser, David E, Westphal, Maximillian S, Stump, Paige A, Stump, Cameron L, Bundschuh, Ralf, Blachly, James S, Yan, Pearlly
יצא לאור 2014

PrEMeR-CG: inferring nucleotide level DNA methylation values from MethylCap-seq data

מאת Frankhouser, David E., Murphy, Mark, Blachly, James S., Park, Jincheol, Zoller, Mike W., Ganbat, Javkhlan-Ochir, Curfman, John, Byrd, John C., Lin, Shili, Marcucci, Guido, Yan, Pearlly, Bundschuh, Ralf
הוצא לאור ב Bioinformatics (2014)

Structural characterization of NRAS isoform 5

מאת Markowitz, Joseph, Mal, Tapas K., Yuan, Chunhua, Courtney, Nicholas B., Patel, Mitra, Stiff, Andrew R., Blachly, James, Walker, Christopher, Eisfeld, Ann‐Kathrin, de la Chapelle, Albert, Carson, William E.
הוצא לאור ב Protein Sci (2016)

Adult acute myeloid leukemia with trisomy 11 as the sole abnormality is characterized by the presence of five distinct gene mutations: MLL-PTD, DNMT3A, U2AF1, FLT3-ITD and IDH2

מאת Eisfeld, Ann-Kathrin, Kohlschmidt, Jessica, Mrózek, Krzysztof, Blachly, James S., Nicolet, Deedra, Kroll, Karl, Orwick, Shelley, Carroll, Andrew J., Stone, Richard M., de la Chapelle, Albert, Byrd, John C., Bloomfield, Clara D.
הוצא לאור ב Leukemia (2016)

Persistence of DNMT3A R882 mutations during remission does not adversely affect outcomes of patients with acute myeloid leukaemia

מאת Bhatnagar, Bhavana, Eisfeld, Ann-Kathrin, Nicolet, Deedra, Mrózek, Krzysztof, Blachly, James S., Orwick, Shelley, Lucas, David M., Kohlschmidt, Jessica, Blum, William, Kolitz, Jonathan E., Stone, Richard M., Bloomfield, Clara D., Byrd, John C.
הוצא לאור ב Br J Haematol (2016)

Novel SF3B1 in-frame deletions result in aberrant RNA splicing in CLL patients

מאת Agrawal, Anant A., Seiler, Michael, Brinton, Lindsey T., Mantel, Rose, Lapalombella, Rosa, Woyach, Jennifer A., Johnson, Amy J., Zhu, Ping, Warmuth, Markus, Yu, Lihua, Byrd, John C., Smith, Peter G., Blachly, James S., Buonamici, Silvia
הוצא לאור ב Blood Adv (2017)

Immunoglobulin transcript sequence and somatic hypermutation computation from unselected RNA-seq reads in chronic lymphocytic leukemia

מאת Blachly, James S., Ruppert, Amy S., Zhao, Weiqiang, Long, Susan, Flynn, Joseph, Flinn, Ian, Jones, Jeffrey, Maddocks, Kami, Andritsos, Leslie, Ghia, Emanuela M., Rassenti, Laura Z., Kipps, Thomas J., de la Chapelle, Albert, Byrd, John C.
הוצא לאור ב Proc Natl Acad Sci U S A (2015)

Mutational landscape and gene-expression patterns in adult acute myeloid leukemias with monosomy 7 as a sole abnormality

מאת Eisfeld, Ann-Kathrin, Kohlschmidt, Jessica, Mrózek, Krzysztof, Volinia, Stefano, Blachly, James S., Nicolet, Deedra, Oakes, Christopher, Kroll, Karl, Orwick, Shelley, Carroll, Andrew J., Stone, Richard M., Byrd, John C., de la Chapelle, Albert, Bloomfield, Clara D.
הוצא לאור ב Cancer Res (2016)

Synergistic effect of BCL2 and FLT3 co-inhibition in acute myeloid leukemia

מאת Brinton, Lindsey T., Zhang, Pu, Williams, Katie, Canfield, Daniel, Orwick, Shelley, Sher, Steven, Wasmuth, Ronni, Beaver, Larry, Cempre, Casey, Skinner, Jordan, Cannon, Matthew, Govande, Mukul, Harrington, Bonnie, Lehman, Amy, Byrd, John C., Lapalombella, Rosa, Blachly, James S.
הוצא לאור ב J Hematol Oncol (2020)

Preclinical activity and a pilot phase I study of pacritinib, an oral JAK2/FLT3 inhibitor, and chemotherapy in FLT3-ITD-positive AML

מאת Jeon, Jae Yoon, Zhao, Qiuhong, Buelow, Daelynn R., Phelps, Mitch, Walker, Alison R., Mims, Alice S., Vasu, Sumithira, Behbehani, Gregory, Blachly, James, Blum, William, Klisovic, Rebecca B., Byrd, John C., Garzon, Ramiro, Baker, Sharyn D., Bhatnagar, Bhavana
הוצא לאור ב Invest New Drugs (2019)