Mutation patterns identify adult patients with de novo acute myeloid leukemia aged 60 years or older who respond favorably to standard chemotherapy: an analysis of Alliance studies

Thus far, only 5–15% of AML patients aged ≥60 years are cured with chemotherapy. Identification of patients who are less (more) likely to respond to standard chemotherapy might enable early risk stratification toward alternative treatment regimens. We used a next-generation sequencing panel of 80 ca...

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Détails bibliographiques
Publié dans:Leukemia
Auteurs principaux: Eisfeld, Ann-Kathrin, Kohlschmidt, Jessica, Mrózek, Krzysztof, Blachly, James S., Walker, Christopher J., Nicolet, Deedra, Orwick, Shelley, Maharry, Sophia E., Carroll, Andrew J., Stone, Richard M., de la Chapelle, Albert, Wang, Eunice S., Kolitz, Jonathan E., Powell, Bayard L., Byrd, John C., Bloomfield, Clara D.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992022/
https://ncbi.nlm.nih.gov/pubmed/29563537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-018-0068-2
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