Mutation patterns identify adult patients with de novo acute myeloid leukemia aged 60 years or older who respond favorably to standard chemotherapy: an analysis of Alliance studies

Thus far, only 5–15% of AML patients aged ≥60 years are cured with chemotherapy. Identification of patients who are less (more) likely to respond to standard chemotherapy might enable early risk stratification toward alternative treatment regimens. We used a next-generation sequencing panel of 80 ca...

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Publicado en:Leukemia
Autores principales: Eisfeld, Ann-Kathrin, Kohlschmidt, Jessica, Mrózek, Krzysztof, Blachly, James S., Walker, Christopher J., Nicolet, Deedra, Orwick, Shelley, Maharry, Sophia E., Carroll, Andrew J., Stone, Richard M., de la Chapelle, Albert, Wang, Eunice S., Kolitz, Jonathan E., Powell, Bayard L., Byrd, John C., Bloomfield, Clara D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992022/
https://ncbi.nlm.nih.gov/pubmed/29563537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-018-0068-2
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