Mutational landscape and clinical outcome of patients with de novo acute myeloid leukemia and rearrangements involving 11q23/KMT2A

Balanced rearrangements involving the KMT2A gene, located at 11q23, are among the most frequent chromosome aberrations in acute myeloid leukemia (AML). Because of numerous fusion partners, the mutational landscape and prognostic impact of specific 11q23/KMT2A rearrangements are not fully understood....

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Proc Natl Acad Sci U S A
मुख्य लेखकों: Bill, Marius, Mrózek, Krzysztof, Kohlschmidt, Jessica, Eisfeld, Ann-Kathrin, Walker, Christopher J., Nicolet, Deedra, Papaioannou, Dimitrios, Blachly, James S., Orwick, Shelley, Carroll, Andrew J., Kolitz, Jonathan E., Powell, Bayard L., Stone, Richard M., de la Chapelle, Albert, Byrd, John C., Bloomfield, Clara D.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2020
विषय:
Biological Sciences
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7584992/
https://ncbi.nlm.nih.gov/pubmed/33020282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2014732117
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