Complex karyotype in de novo acute myeloid leukemia: typical and atypical subtypes differ molecularly and clinically

Complex karyotype (CK) with ≥3 abnormalities is detected in 10-12% of patients with acute myeloid leukemia (AML) and associated with poor prognosis. The most common unbalanced abnormalities found in CK result in loss of material from the 5q, 7q and/or 17p chromosome arms. The presence of 5q, 7q and/...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Leukemia
Main Authors: Mrózek, Krzysztof, Eisfeld, Ann-Kathrin, Kohlschmidt, Jessica, Carroll, Andrew J., Walker, Christopher J., Nicolet, Deedra, Blachly, James S., Bill, Marius, Papaioannou, Dimitrios, Wang, Eunice S., Uy, Geoffrey L., Kolitz, Jonathan E., Powell, Bayard L., Blum, William, Stone, Richard M., Byrd, John C., Bloomfield, Clara D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6609457/
https://ncbi.nlm.nih.gov/pubmed/30737482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-019-0390-3
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados