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Inflammatory pre-conditioning restricts the seeded induction of α-synuclein pathology in wild type mice
BACKGROUND: Cell-to-cell transmission of α-synuclein (αSyn) is hypothesized to play an important role in disease progression in synucleinopathies. This process involves cellular uptake of extracellular amyloidogenic αSyn seeds followed by seeding of endogenous αSyn. Though it is well known that αSyn...
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| Publicat a: | Mol Neurodegener |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5210310/ https://ncbi.nlm.nih.gov/pubmed/28049533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-016-0142-z |
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