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Inflammatory pre-conditioning restricts the seeded induction of α-synuclein pathology in wild type mice
BACKGROUND: Cell-to-cell transmission of α-synuclein (αSyn) is hypothesized to play an important role in disease progression in synucleinopathies. This process involves cellular uptake of extracellular amyloidogenic αSyn seeds followed by seeding of endogenous αSyn. Though it is well known that αSyn...
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| 發表在: | Mol Neurodegener |
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| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5210310/ https://ncbi.nlm.nih.gov/pubmed/28049533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-016-0142-z |
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