Inflammatory pre-conditioning restricts the seeded induction of α-synuclein pathology in wild type mice

BACKGROUND: Cell-to-cell transmission of α-synuclein (αSyn) is hypothesized to play an important role in disease progression in synucleinopathies. This process involves cellular uptake of extracellular amyloidogenic αSyn seeds followed by seeding of endogenous αSyn. Though it is well known that αSyn...

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Detaylı Bibliyografya
Yayımlandı:Mol Neurodegener
Asıl Yazarlar: Koller, Emily J., Brooks, Mieu M. T., Golde, Todd E., Giasson, Benoit I., Chakrabarty, Paramita
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5210310/
https://ncbi.nlm.nih.gov/pubmed/28049533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-016-0142-z
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