Chargement en cours...
The interaction between ALKBH2 DNA repair enzyme and PCNA is direct, mediated by the hydrophobic pocket of PCNA and perturbed in naturally-occurring ALKBH2 variants
Human AlkB homolog 2 (ALKBH2) is a DNA repair enzyme that catalyzes the direct reversal of DNA methylation damage through oxidative demethylation. While ALKBH2 colocalizes with proliferating cell nuclear antigen (PCNA) in DNA replication foci, it remains unknown whether these two proteins alone form...
Enregistré dans:
| Publié dans: | DNA Repair (Amst) |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5206904/ https://ncbi.nlm.nih.gov/pubmed/26408825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2015.09.008 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|