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Human ALKBH7 is required for alkylation and oxidation-induced programmed necrosis

Programmed necrosis has emerged as a crucial modulator of cell death in response to several forms of cellular stress. In one form of programmed necrotic cell death, induced by cytotoxic alkylating agents, hyperactivation of poly-ADP-ribose polymerase (PARP) leads to cellular NAD and ATP depletion, m...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Fu, Dragony, Jordan, Jennifer J., Samson, Leona D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672644/
https://ncbi.nlm.nih.gov/pubmed/23666923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.215533.113
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