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Human ALKBH7 is required for alkylation and oxidation-induced programmed necrosis
Programmed necrosis has emerged as a crucial modulator of cell death in response to several forms of cellular stress. In one form of programmed necrotic cell death, induced by cytotoxic alkylating agents, hyperactivation of poly-ADP-ribose polymerase (PARP) leads to cellular NAD and ATP depletion, m...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3672644/ https://ncbi.nlm.nih.gov/pubmed/23666923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.215533.113 |
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