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Roles of Aag,Alkbh2, and Alkbh3 in the Repair of Carboxymethylated and Ethylated Thymidine Lesions

Environmental and endogenous genotoxic agents can result in a variety of alkylated and carboxymethylated DNA lesions, includingN3-ethylthymidine (N3-EtdT), O(2)-EtdT, O(4)-EtdT as well as N3-carboxymethylthymidine (N3-CMdT) and O(4)-CMdT. By using non-replicative double-stranded vectors harboring a...

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Bibliografiske detaljer
Udgivet i:ACS Chem Biol
Main Authors: You, Changjun, Wang, Pengcheng, Nay, Stephanie L., Wang, Jianshuang, Dai, Xiaoxia, O’Connor, Timothy R., Wang, Yinsheng
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038138/
https://ncbi.nlm.nih.gov/pubmed/26930515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00085
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