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Replication studies of carboxymethylated DNA lesions in human cells

Metabolic activation of some N-nitroso compounds (NOCs), an important class of DNA damaging agents, can induce the carboxymethylation of nucleobases in DNA. Very little was previously known about how the carboxymethylated DNA lesions perturb DNA replication in human cells. Here, we investigated the...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Wu, Jun, Wang, Pengcheng, Li, Lin, Williams, Nicole L., Ji, Debin, Zahurancik, Walter J., You, Changjun, Wang, Jianshuang, Suo, Zucai, Wang, Yinsheng
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499590/
https://ncbi.nlm.nih.gov/pubmed/28531304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx442
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