Replication studies of carboxymethylated DNA lesions in human cells

Metabolic activation of some N-nitroso compounds (NOCs), an important class of DNA damaging agents, can induce the carboxymethylation of nucleobases in DNA. Very little was previously known about how the carboxymethylated DNA lesions perturb DNA replication in human cells. Here, we investigated the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: Wu, Jun, Wang, Pengcheng, Li, Lin, Williams, Nicole L., Ji, Debin, Zahurancik, Walter J., You, Changjun, Wang, Jianshuang, Suo, Zucai, Wang, Yinsheng
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2017
Pynciau:
Genome Integrity, Repair and Replication
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499590/
https://ncbi.nlm.nih.gov/pubmed/28531304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx442
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