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In Vitro Replication Studies of Carboxymethylated DNA Lesions with Saccharomyces cerevisiae Polymerase η
Humans are exposed to N-nitroso compounds (NOCs) both endogenously and exogenously from a number of environmental sources, and NOCs are both mutagenic and carcinogenic. After metabolic activation, some NOCs can induce carboxymethylation of nucleobases through a diazoacetate intermediate, which could...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3164846/ https://ncbi.nlm.nih.gov/pubmed/21809836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2007417 |
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