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Accurate and Efficient Bypass of 8,5'-Cyclopurine-2'-Deoxynucleosides by Human and Yeast DNA Polymerase η

Reactive oxygen species (ROS), which can be produced during normal aerobic metabolism, can induce the formation of tandem DNA lesions, including 8,5'-cyclo-2'-deoxyadenosine (cyclo-dA) and 8,5'-cyclo-2'-deoxyguanosine (cyclo-dG). Previous studies have shown that cyclo-dA and cycl...

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Detalhes bibliográficos
Main Authors: Swanson, Ashley L., Wang, Jianshuang, Wang, Yinsheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423583/
https://ncbi.nlm.nih.gov/pubmed/22768970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx3001576
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