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The efficiency and fidelity of 8-oxo-guanine bypass by DNA polymerases δ and η
A DNA lesion created by oxidative stress is 7,8-dihydro-8-oxo-guanine (8-oxoG). Because 8-oxoG can mispair with adenine during DNA synthesis, it is of interest to understand the efficiency and fidelity of 8-oxoG bypass by DNA polymerases. We quantify bypass parameters for two DNA polymerases implica...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2685079/ https://ncbi.nlm.nih.gov/pubmed/19282446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp103 |
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