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Loop 1 modulates the fidelity of DNA polymerase λ
Differences in the substrate specificity of mammalian family X DNA polymerases are proposed to partly depend on a loop (loop 1) upstream of the polymerase active site. To examine if this is the case in DNA polymerase λ (pol λ), here we characterize a variant of the human polymerase in which nine res...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2938210/ https://ncbi.nlm.nih.gov/pubmed/20435673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq261 |
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