Substrate-induced DNA strand misalignment during catalytic cycling by DNA polymerase λ

The simple deletion of nucleotides is common in many organisms. It can be advantageous when it activates genes beneficial to microbial survival in adverse environments, and deleterious when it mutates genes relevant to survival, cancer or degenerative diseases. The classical idea is that simple dele...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Bebenek, Katarzyna, Garcia-Diaz, Miguel, Foley, Meredith C, Pedersen, Lars C, Schlick, Tamar, Kunkel, Thomas A
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2008
Sujets:
Scientific Report
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278112/
https://ncbi.nlm.nih.gov/pubmed/18369368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.33
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires