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Substrate-induced DNA strand misalignment during catalytic cycling by DNA polymerase λ
The simple deletion of nucleotides is common in many organisms. It can be advantageous when it activates genes beneficial to microbial survival in adverse environments, and deleterious when it mutates genes relevant to survival, cancer or degenerative diseases. The classical idea is that simple dele...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2008
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2278112/ https://ncbi.nlm.nih.gov/pubmed/18369368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.33 |
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