Substrate-induced DNA strand misalignment during catalytic cycling by DNA polymerase λ

The simple deletion of nucleotides is common in many organisms. It can be advantageous when it activates genes beneficial to microbial survival in adverse environments, and deleterious when it mutates genes relevant to survival, cancer or degenerative diseases. The classical idea is that simple dele...

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Detaylı Bibliyografya
Asıl Yazarlar: Bebenek, Katarzyna, Garcia-Diaz, Miguel, Foley, Meredith C, Pedersen, Lars C, Schlick, Tamar, Kunkel, Thomas A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2008
Konular:
Scientific Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278112/
https://ncbi.nlm.nih.gov/pubmed/18369368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.33
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