Substrate-induced DNA strand misalignment during catalytic cycling by DNA polymerase λ

The simple deletion of nucleotides is common in many organisms. It can be advantageous when it activates genes beneficial to microbial survival in adverse environments, and deleterious when it mutates genes relevant to survival, cancer or degenerative diseases. The classical idea is that simple dele...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Bebenek, Katarzyna, Garcia-Diaz, Miguel, Foley, Meredith C, Pedersen, Lars C, Schlick, Tamar, Kunkel, Thomas A
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2008
Aiheet:
Scientific Report
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278112/
https://ncbi.nlm.nih.gov/pubmed/18369368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.33
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