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Ubiquitinated proliferating cell nuclear antigen activates translesion DNA polymerases η and REV1
In response to DNA damage, the Rad6/Rad18 ubiquitin-conjugating complex monoubiquitinates the replication clamp proliferating cell nuclear antigen (PCNA) at Lys-164. Although ubiquitination of PCNA is recognized as an essential step in initiating postreplication repair, the mechanistic relevance of...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1317920/ https://ncbi.nlm.nih.gov/pubmed/16344468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505949102 |
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