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A novel ubiquitin binding mode in the S. cerevisiae translesion synthesis DNA polymerase η

The ubiquitin binding zinc finger (UBZ) domain in the C-terminal portion of Polη has been found to interact with ubiquitin. However, the affinity between the Polη UBZ and ubiquitin was shown to be low with a previously reported K(d) of 73~81 μM. This low-affinity binding between Polη UBZ and ubiquit...

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Hlavní autoři: Ai, Yongxing, Wang, Jialiang, Johnson, Robert E., Haracska, Lajos, Prakash, Louise, Zhuang, Zhihao
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228521/
https://ncbi.nlm.nih.gov/pubmed/21483899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0mb00355g
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