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Mutations in the Ubiquitin Binding UBZ Motif of DNA Polymerase η Do Not Impair Its Function in Translesion Synthesis during Replication
Treatment of Saccharomyces cerevisiae cells with DNA-damaging agents elicits lysine 164-linked PCNA monoubiquitination by Rad6-Rad18. Recently, a number of ubiquitin (Ub) binding domains (UBDs) have been identified in translesion synthesis (TLS) DNA polymerases and it has been proposed that the UBD...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2168893/ https://ncbi.nlm.nih.gov/pubmed/17709386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01196-07 |
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