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Ubiquitylation of yeast proliferating cell nuclear antigen and its implications for translesion DNA synthesis

The Rad6–Rad18 ubiquitin-conjugating enzyme complex promotes replication through DNA lesions by means of at least three different pathways: the DNA polymerase (Pol) η- and ζ-dependent translesion DNA synthesis (TLS) and a Rad5–Mms2–Ubc13-dependent pathway. In DNA-damaged yeast cells proliferating ce...

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Détails bibliographiques
Auteurs principaux: Haracska, Lajos, Unk, Ildiko, Prakash, Louise, Prakash, Satya
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458909/
https://ncbi.nlm.nih.gov/pubmed/16611731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510924103
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