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Role of DNA polymerase η in the bypass of abasic sites in yeast cells
Abasic (AP) sites are major DNA lesions and are highly mutagenic. AP site-induced mutagenesis largely depends on translesion synthesis. We have examined the role of DNA polymerase η (Polη) in translesion synthesis of AP sites by replicating a plasmid containing a site-specific AP site in yeast cells...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2004
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC506798/ https://ncbi.nlm.nih.gov/pubmed/15284331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh710 |
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