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Role of DNA polymerase η in the bypass of abasic sites in yeast cells

Abasic (AP) sites are major DNA lesions and are highly mutagenic. AP site-induced mutagenesis largely depends on translesion synthesis. We have examined the role of DNA polymerase η (Polη) in translesion synthesis of AP sites by replicating a plasmid containing a site-specific AP site in yeast cells...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhao, Bo, Xie, Zhongwen, Shen, Huiyun, Wang, Zhigang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC506798/
https://ncbi.nlm.nih.gov/pubmed/15284331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh710
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