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Translesion Synthesis of 8,5′-Cyclopurine-2′-deoxynucleosides by DNA Polymerases η, ι, and ζ

Reactive oxygen species can give rise to a battery of DNA damage products including the 8,5′-cyclo-2′-deoxyadenosine (cdA) and 8,5′-cyclo-2′-deoxyguanosine (cdG) tandem lesions. The 8,5′-cyclopurine-2′-deoxynucleosides are quite stable lesions and are valid and reliable markers of oxidative DNA dama...

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Autori principali: You, Changjun, Swanson, Ashley L., Dai, Xiaoxia, Yuan, Bifeng, Wang, Jianshuang, Wang, Yinsheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789955/
https://ncbi.nlm.nih.gov/pubmed/23965998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.480459
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