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Hydrolyzable Tannins Are Iron Chelators That Inhibit DNA Repair Enzyme ALKBH2
Hydrolyzable tannins are a class of polyphenolic compounds commonly found in natural products. In this work, we studied the in vitro inhibitory mechanism of six molecules in this class on ALKBH2, an Fe(II)/α-ketogluta-rate-dependent DNA repair enzyme in the AlkB family. We determined the IC(50) valu...
Gorde:
| Argitaratua izan da: | Chem Res Toxicol |
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| Egile Nagusiak: | , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2019
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6890495/ https://ncbi.nlm.nih.gov/pubmed/31088072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.8b00398 |
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