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Transcriptome Profiling of NIH3T3 Cell Lines Expressing Opsin and the P23H Opsin Mutant Identifies Candidate Drugs for the Treatment of Retinitis Pigmentosa

Mammalian cells are commonly employed in screening assays to identify active compounds that could potentially affect the progression of different human diseases including retinitis pigmentosa (RP), a class of inherited diseases causing retinal degeneration with compromised vision. Using transcriptom...

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Detalhes bibliográficos
Publicado no:Pharmacol Res
Main Authors: Chen, Yuanyuan, Brooks, Matthew J, Gieser, Linn, Swaroop, Anand, Palczewski, Krzysztof
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5205556/
https://ncbi.nlm.nih.gov/pubmed/27838510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2016.10.031
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