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Electrostatic Compensation Restores Trafficking of the Autosomal Recessive Retinitis Pigmentosa E150K Opsin Mutant to the Plasma Membrane

Rhodopsin is the rod photoreceptor G protein-coupled receptor responsible for capturing light. Mutations in the gene encoding this protein can lead to a blinding disease called retinitis pigmentosa, which is inherited frequently in an autosomal dominant manner. The E150K opsin mutant associated with...

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Detalhes bibliográficos
Main Authors: Pulagam, Lakshmi Padmavathi, Palczewski, Krzysztof
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937977/
https://ncbi.nlm.nih.gov/pubmed/20628051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.151407
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